EP09.04: Cardiac dysfunction in fetal growth restriction measured by means of myocardial performance index

Fetal growth restriction (FGR) is accompanied by an increased risk for cardiovascular dysfunction. Myocardial performance index (MPI) may give early hints on diastolic cardiac impairment prior to clinical manifestation. It is easily obtained from the 5-chamber-view during Doppler ultrasound examination. In this prospective case control study the MPI was measured in 23 fetuses with FGR < 3. percentile and compared to 20 appropriate for gestational age (AGA) fetuses between 24-39 weeks of gestation. In addition, the relationship between the cerebroplacental ratio (CPR) and MPI was examined. The FGR group showed a significantly increased MPI in comparison to the control group (0,42 vs. 0,53, p < 0,001). A correlation with a pathological CPR could not be identified. MPI reveals cardiac dysfunction in FGR decisively before measurable fetal Doppler pathologies are detectable. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.