Braf Non-V600e Mutated Metastatic Colorectal Cancer In A Young Patient: Discussion From A Case Report
CASE REPORTS IN ONCOLOGY(2019)
摘要
We report the case of a 32-year-old man with a caecal adenocarcinoma with major lymph node extension and peritoneal carcinomatosis, presenting a BRAF-K601E mutation. A triplet (5FU plus oxaliplatin plus irinotecan) combination with bevacizumab achieved tumor control but the disease progressed immediately after cessation and the patient died 8 months after the diagnosis. A short review of BRAF non-V600E mutations shows that outcome and clinical features depend on the mutation.
更多查看译文
关键词
Metastatic colorectal cancer, Prognosis, Molecular characterization, BRAF mutation
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要