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Role of B cells and antibodies in multiple sclerosis

Pitchaya Wanleenuwat,Piotr Iwanowski

Multiple Sclerosis and Related Disorders（2019）

Cited 24|Views2
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Abstract
•B cells contribute to multiple sclerosis (MS) pathogenesis.•Antibody-dependent and independent mechanisms are involved.•Defects in peripheral tolerance may lead to MS development.•B cell depletion reduces relapse episodes and slows progression.
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Key words
Multiple sclerosis,B cells,Antibodies,Neuroinflammation,Demyelination
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