Production Of Tetrahydrocurcumin From Curcumin By Cultured Plant Cells And Inhibitory Effects Of Curcuminoids On Nf-Kappa B Activity

Kei Shimoda,Naoji Kubota,Yuya Fujitaka,Hiroki Hamada,Manami Inoue,Hatsuyuki Hamada,Masayoshi Yanagi,Tatsuya Onishi

NATURAL PRODUCT COMMUNICATIONS（2019）

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摘要

Biotransformation of curcumin was investigated using cultured plant cells of Morus sp. Cultured Morus cells converted curcumin into dihydrocurcumin and tetrahydrocurcumin. The activity of nuclear factor-kappa B was inhibited by curcumin and tetrahydrocurcumin.

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关键词

biotransformation, reduction, Morus sp, curcumin, tetrahydrocurcumin, NF-kappa B

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