Mitracarpus frigidus is active against Salmonella enterica species including the biofilm form

•The methanolic extract of Mitracarpus frigidus was active against quinolone-resistant and susceptible Salmonella strains.•The methanolic extract of Mitracarpus frigidus was effective against Salmonella biofilms.•The methanolic extract of Mitracarpus frigidus affected Salmonellaplasma membranes.•The methanolic extract of Mitracarpus frigidus exhibited synergism with erythromycin with potential use in combination therapy.•The methanolic extract of Mitracarpus frigidus activity may be related to the compounds already identified in the extract.