72 - Predicting Response to Resensitization of Radioiodine Resistant Thyroid Cancer With Whole Exome Sequencing

Kirstie Lithgow, Helen Huang, Denise Chan,Moosa Khalil, Mike Bristow, Vincent Dinculescu,Markus Eszlinger,Vicky Parkins,Ralf Paschke

Canadian Journal of Diabetes(2019)

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Abstract
Inhibition of MAPK signalling can restore sensitivity to radioactive iodine (RI) in patients with radioiodine resistant thyroid cancer. Tramatenib has recently been used to resensitize RI resistant RAS positive or RAS and BRAF negative thyroid carcinomas.
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Key words
radioiodine resistant thyroid cancer,sequencing,whole exome
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