Neuroimmune crosstalk in central nervous system injury-induced infection and pharmacological intervention
Brain Research Bulletin（2019）
Abstract
•The incidence and treatment of infection after CNS injury.•Mechanism of intestinal bacterial translocation mediated infection after CNS injury.•Interaction of SNS, PNS and HPA axis in CNS injury induced immunodeficiency and infection.•Pharmacological intervention and immunomodulatory therapies the CNS injury induced infection.
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Key words
Central nervous system injury,Immunosuppression,Sympathetic nervous system,Parasympathetic nervous system,HPA axis,Intestinal flora
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