Graphene oxide as a green carbon material for cross-coupling of indoles with ethers via oxidation and the Friedel–Crafts reaction

Mild reaction conditions were developed to access 3,3'-bisindolylmethane derivatives with excellent regioselectivity at 25 degrees C based on a new graphene oxide (GO)-promoted alkylation strategy. To the best of our knowledge, these results constitute the first example of using a GO-based material as a carbon material to facilitate C(sp(2))-C(sp(3)) bond formation.