A general, enantioselective synthesis of 2-substituted thiomorpholines and thiomorpholine 1,1-dioxides

Tetrahedron Letters（2019）

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摘要

•First enantioselective methodology for chiral, C2-subsituted thiomorpholines.•Rapid access to chiral thiomorpholine 1,1-dioxides.•Control of stereochemistry based on organocatalyst employed.•General protocol affording high % ee.

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关键词

Thiomorpholine,Thiomorpholine 1,1-dioxide,Enantioselective,Organocatalysis

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