Iodine mediated rearrangement of tetraarylpiperidin-4-ones: Synthesis, structure analysis and biological studies of 5-aryl-2-methoxy-2,4-diphenyl-1H-pyrrole-3-ones

An interesting iodine/methanol mediated rearrangement of tetraaylpiperidin-4-ones to 2-methoxy-2,4,5-triaryl-1H-pyrrole-3-ones is described. The structural features of the products are investigated by spectral data and single crystal X-ray analysis. The antifungal, antibacterial and antioxidant characteristics of the synthesized compounds have been studied.