Niobium Pentachloride Mediated (Hetero)aromatic Aldehyde Friedel–Crafts Hydroxyalkylation with Arenes: An Efficient Strategy to Synthesize Triarylmethanes
SYNTHESIS-STUTTGART(2019)
摘要
Niobium pentachloride is an efficient and useful Lewis acid to conduct Friedel-Crafts hydroxyalkylation between arenes and (hetero)aromatic aldehydes, to generate triarylmethanes. This practical methodology offers several advantages, such as short reaction time, mild experimental conditions, and excellent yields.
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关键词
triarylmethanes,niobium pentachloride,Friedel-Crafts hydroxyalkylation,carbocations,(hetero)aromatic aldehydes
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