Secondary Hematologic Neoplasms After Childhood Solid Cancer Treatment in a Single Reference Cancer Center

Marcia Schramm,Claudete Klumb,Alexandre Apa,Nathalia Grigorovski,Teresa Fernandez, Mileine Garabal, Gisele Caldas

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA（2019）

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Abstract

Childhood cancer overall survival has increased due to treatment and outcomes improvements. However, long-term adverse effects are a challenge for this population. Secondary hematologic neoplasm (SHN) is one of the serious complications of solid tumor treatment (chemotherapy and radiotherapy). Acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) are the most common SHN.

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Key words

solid tumor,therapy,secondary hematologic neoplasm,childhood,AML,acute myeloid leukemia

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