Synthesis and Structure of 4-Het(aryl)-3,5,5-trimethoxycarbonyl-2-pyrrolidones

N. V. Gorodnicheva,E. S. Ostroglyadov,O. S. Vasil’yeva,S. V. Makarenko

Russian Journal of General Chemistry（2019）

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摘要

Condensation of 2-het(aryl)-1,1-dimethoxycarbonylethenes with acetylaminomalonic acid ester afforded (3 R *,4 S *)-4-(4-methoxyphenyl)-, (3 R *,4 S *)-4-(3,4-methylenedioxyphenyl)-, (3 R *,4 S *)-4-(4-dimethylaminophenyl)-, (3 R *,4 S *)-4-(2-furyl)-, (3 R *,4 S *)-4-(indol-3-yl)-, (3 R *,4 S *)-4-(1-methylindol-3-yl)-, and (3 R *,4 S *)-4-(1-benzylindol-3-yl)-3,5,5-tris(methoxycarbonyl)-2-pyrrolidones.

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关键词

heterocyclic compounds,2-pyrrolidone,pyrrolidone-2-carboxylic acids esters

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