Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS(2019)
摘要
The Translational Brain Mapping Program at the University of Rochester is an interdisciplinary effort that integrates cognitive science, neurophysiology, neuroanesthesia, and neurosurgery. Patients who have tumors or epileptogenic tissue in eloquent brain areas are studied preoperatively with functional and structural MRI, and intraoperatively with direct electrical stimulation mapping. Post-operative neural and cognitive outcome measures fuel basic science studies about the factors that mediate good versus poor outcome after surgery, and how brain mapping can be further optimized to ensure the best outcome for future patients. In this article, we describe the interdisciplinary workflow that allows our team to meet the synergistic goals of optimizing patient outcome and advancing scientific understanding of the human brain.
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关键词
Neuroscience,Issue 150,brain tumor,brain surgery,neurosurgery,brain mapping,translational brain mapping,fMRI,DTI,functional MRI,MRI,Diffusion Tensor Imaging,awake brain surgery,awake craniotomy,human brain map,direct electrical stimulation,epilepsy,glioma,glioblastoma,frontal aslant tract,SMA syndrome,motor cortex,cortical language centers,eloquent cortex
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