Leptin Gene Expression In Males Epicardial Adipose Tissue In Coronary Heart Disease

Background and Aims: High level of paracrine activity of visceral adipose tissue is associated with the risk of atherosclerosis. Epicardial adipose tissue (EAT) synthesizes numerous adipocytokines and pro-inflammatory mediators, local and systemic effects of which may be important in the development of atherosclerosis of the coronary arteries. In the pathogenesis of atherosclerosis, we discuss the role adipocytokines such as leptin.Evaluate leptin gene expression in EAT in coronary heart disease (CHD) males.