Recent Progress In The Copper-Catalyzed Cascade Cyclization Involving Intramolecular Hydroamination Of Terminal Alkynes
SYNLETT(2019)
Abstract
Transition-metal-catalyzed cascade cyclization initiated by intramolecular alkyne hydroamination has received considerable attention over the past decade and has been widely used in the rapid construction of a diverse array of valuable complex N-heterocycles. Recent progress in this area is reviewed with an emphasis on the cheap and environmentally benign copper-catalyzed cascade cyclization of terminal alkynes.
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Key words
copper catalysis,hydroamination,alkynes,cascade reactions,cyclization,heterocycles
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