Non-Leishmania Parasite in Fatal Visceral Leishmaniasis-Like Disease, Brazil.

Sandra R Maruyama, Alynne K M de Santana,Nayore T Takamiya, Talita Y Takahashi,Luana A Rogerio, Caio A B Oliveira,Cristiane M Milanezi, Viviane A Trombela,Angela K Cruz,Amélia R Jesus,Aline S Barreto,Angela M da Silva,Roque P Almeida,José M Ribeiro,João S Silva

EMERGING INFECTIOUS DISEASES（2019）

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摘要

Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis-like illness in Brazil. The parasites infected mice and reproduced the patient's clinical manifestations. Molecular epidemiologic studies are needed to ascertain whether a new infectious disease is emerging that can be confused with leishmaniasis.

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关键词

Brazil,Crithidia-related,Visceral leishmaniasis–like,genome sequencing,parasites,sand flies,vector-borne infections,whole-genome sequencing

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