Molecular characterization of Schistosoma mansoni tegument annexins and comparative analysis of antibody responses following parasite infection.
Molecular and Biochemical Parasitology（2019）
Abstract
•Structural and immunobiochemical characterization of four homologous annexins expressed in Schistosoma mansoni tegument.•Gene expression profiles of four homologous annexins throughout the life cycle of the schistosome.•Expression and immunolocalization of annexin molecules in the tegument of Schistosoma mansoni.•Recombinant annexins are rich in alpha-helices and the proteins are recognized by the sera of mice infected with S. mansoni.
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Key words
Annexin,Immunoreactivity,Parasite–host interactions,Schistosoma mansoni,Schistosomiasis,Immunolocalization
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