Patient-Reported Neuropsychiatric Outcomes of Long-Term Survivors after Chimeric Antigen Receptor-T Cell Therapy.

Biology of Blood and Marrow Transplantation(2020)

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摘要
•Overall, long-term survivors after chimeric antigen receptor (CAR) T cell therapy report good mental health.•A subset of patients may experience psychiatric symptoms or cognitive impairment.•Allogeneic hematopoietic cell transplantation before or after CAR T cells does not affect long-term mental health.•Older age is associated with better mental health in long-term CAR T cell survivors.•Cognitive difficulties are associated with worse global mental and physical health.
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关键词
CD19-targeted CAR T cells,Late events,Patient-reported outcomes
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