Interleukin-18 in patients with acute coronary syndromes.

Axel Åkerblom,Stefan K James,Tatevik G Lakic,Richard C Becker,Christopher P Cannon,Philippe G Steg,Anders Himmelmann,Hugo A Katus,Robert F Storey,Lars Wallentin,W Douglas Weaver,Agneta Siegbahn

Clinical cardiology（2019）

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摘要

In ACS patients, IL-18 concentrations increased after the acute event and remained increased for 6 months. Baseline IL-18 levels were significantly associated with CV mortality, independent of clinical characteristics and indicators of renal/cardiac dysfunction but this association was attenuated after adjustment for multiple biomarkers.

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关键词

acute coronary syndrome,inflammation,morbidity,mortality,myocardial infarction

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