Comparison of the usefulness of a targeted temperature management protocol before and after modification: A single-centre retrospective study

Background: After the targeted temperature management (TTM) trial in 2014, guidelines for cardiac arrest recommend maintaining a target temperature between 32 °C and 36 °C after return of spontaneous circulation (ROSC). We established an original TTM protocol that included maintaining a temperature of 35 °C for our institute, as this temperature provides a large safety margin for temperature variation and is expected to reduce the comorbidity with TTM. This is a single-centre retrospective study that assessed the usefulness of the new 35 °C TTM protocol in comparison with the conventional 34 °C or 36 °C protocol.