Il-1 Pathway Inhibition Attenuates Vascular Smooth Muscle Cell Phenotypic Switching To A Macrophage-Like State During Aortic Aneurysm Formation

Morgan D. Salmon,William Montgomery,Michael D. Spinosa,Delphine Gomez,Gary K. Owens,Ashish K. Sharma,Gilbert R. Upchurch,Gorav Ailawadi

Circulation（2017）

引用 22|浏览9

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摘要

Introduction: Aortic aneurysms(AAs) are characterized by inflammation, cytokine upregulation, smooth muscle cell(SMC) modulation, macrophage activation and matrix degradation. IL-1 has been shown t...

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关键词

Abdominal aortic aneurysm,Aortic aneurysm,Inflammation,Smooth muscle

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