Investigating The Effect Of A High Fat Meal And Prolonged Sitting On Executive Function: A Pilot Study
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE(2019)
摘要
Prolonged periods of sitting have been shown to reduce cerebral blood flow and autoregulation, which may subsequently impair executive function. Similarly, the consumption of a high-fat diet can negatively impact cerebral perfusion. However, whether prolonged sitting combined with a high fat meal additionally impairs both executive function and cerebral perfusion is unknown. PURPOSE: To investigate the effects of consuming a high-fat meal followed by 3 hours of prolonged sitting on executive function and cerebral perfusion. METHODS: Five young healthy males (Age: 22.8 ± 2.9 yrs; stature 177.7 ± 6.4 cm; mass 78.9 ± 14.3 kg), from a target of 18, were recruited. Following familiarisation, participants completed two randomised sessions of 3 hours of prolonged sitting following the consumption of a high-fat (HF) and low-fat (LF) meal. Each visit was separated by a minimum of 2 and maximum of 7 days. Participants completed a Stroop test (containing both congruent and incongruent trials) and trail-making test (TMT) both pre- and post- sitting period. The TMT consists of two parts, A and B. Continuous wave near-infrared spectroscopy (cw-NIRS) was used to measure cerebral perfusion at AF4 both before (baseline) and throughout each trial. Data was analyzed using two-way repeated measures analysis of variance. Alpha was set at P < 0.1 a priori for preliminary analyses. RESULTS: There were no significant differences between or within trials for completion time for Stroop and TMT part A. Completion time for TMT part B was significantly (p = 0.078, d = 2.2) faster in the low-fat condition compared to HF condition (16.4 ± 4 s vs. 21.6 ± 0.7 s). There were no significant differences in cerebral perfusion between or within groups (p = 0.201). CONCLUSIONS: These preliminary findings suggest that the consumption of a high-fat meal may negatively impact core executive functions measured by TMT Part B, namely working memory and task-switching ability. However, cerebral perfusion, as measured by cw-NIRS, failed to identify a mechanism. This may be a consequence of limited statistical power given the sample size, or uncertainties regarding the sensitivity of cw-NIRS when measuring cerebral perfusion.
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关键词
executive function,high fat meal,prolonged sitting,pilot study
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