SUN-310 URINARY EXTRACELLULAR VESICLES REFLECT THE PATHOLOGY OF DIABETIC NEPHROPATHY

F. Cai, W. Wu, M. Cheng,J. Huang, Y. Jia,D. Miao, J. Tang, S. Wang,G. Liu, L. Yang

Kidney International Reports（2019）

Cited 0|Views131

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Abstract

Diabetic nephropathy (DN) involves the injury of podocytes, tubular epithelium, and endothelium. These cells release substantial extracellular vesicles (EVs) into urine, which are supposed to increase when their parent cells encounter stressed conditions. We therefore hypothesize that various populations of urinary EVs could reflect the pathological features of DN, thus might help differentiate patients with DN from those with non-DN proteinuria.

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Key words

urinary extracellular vesicles

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