OUTDOOR TEMPERATURE AND ARTERIAL STIFFNESS AS FACTORS OF INFLUENCING OF NOCTURNAL BLOOD PRESSURE FALL IN UNTREATED PATIENTS WITH HIGH NORMAL BLOOD PRESSURE IN SUMMER

Objective: The nocturnal blood pressure fall of blood pressure (BP) and unfavorable circadian BP rhythms are associated with the risk of adverse outcomes. The aim of our study was to estimate factors associated with reduced-dipper's and reverse-dipper's status of 24 hour BP (BP24) in untreated patients with high normal BP in summer include outdoor temperature and arterial stiffness (AS). Design and method: The patients from the ambulatory BP monitoring (ABPM) database (>300 patients) were selected according to the following criteria: age 40–79 years, absence of any antihypertensive treatment, clinical BP (CBP) 130–139 mmHg and/or 85–89 mmHg, ABPM with AS24 estimations in summer, medical history and anthropometry data. The standard statistical methods and multivariate analysis were used. Results: The 226 patients were enrolled. Median ambulatory diastolic BP was above the upper limit of normally (74.3% patients with masked hypertension). The main characteristics of patients are presented in Table1. Predictors of the reduced-dipper's+reverse-dipper's status of BP are presented in Table2.Conclusions: AS, the outdoor temperature, and systolic BP in orthostasis are factors of unfavorable types of nocturnal BP fall in untreated patients with high normal CBP in summer. Further research is needed including the assessment of cardiovascular prognosis in these patients.