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Experimental evidences on the role of silica nanoparticles surface morphology on the loading, release and activity of three proteins

Giulia Zampini,Davide Matino,Giulia Quaglia,Luigi Tarpani,Marco Gargaro, Federica Cecchetti,Alfonso Iorio,Francesca Fallarino,Loredana Latterini

Microporous and Mesoporous Materials（2019）

Cited 11|Views12
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Abstract
Silica nanomaterials have been proposed as promising candidates for the delivery of drugs, including purified proteins, thus a systematic investigation on the role of silica surface porosity, for optimal protein loading and release, represents an urgent need.
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Key words
Porous silica nanoparticles,Protein release,Bovine serum albumin,Myoglobin,Factor VIII
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