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Alliin protects against inflammatory bowel disease by preserving the gene expression in colonic epithelial cells rather than altering gut microbiota

Xuanwei Li,Jianming Luo,Cheng Zhang,Liu Liu,Shiyi Ou,Guangwen Zhang,Xichun Peng

Journal of Functional Foods（2019）

Cited 3|Views20
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Abstract
•Alliin prevents colon shortening caused by colitis.•Alliin relieves inflammation by lowering myeloperoxidase activity.•The protective effect of alliin does not attribute to gut microbiota alteration.•Alliin sustains the expression of 23 genes in colonic epithelial cells.
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Key words
Alliin,Inflammatory bowel disease,Gut microbiota,Colonic epithelial cells,Gene expression
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