AB0199 ASSESSING DISABILITY AND QUALITY OF LIFE IN ALGERIAN SYSTEMIC SCLEROSIS PATIENTS: CONSTRUCT VALIDITIES OF THE ARAB HAND FUNCTION INDEX AND HEALTH ASSESSMENT QUESTIONNAIRE (HAQ)

Objectives To assess the construct validity of the Arab Hand Function Index (AHFI), an Arabic and adapted version of the Cochin hand Functional scale (CHFS) and an Arabic version of the Health Assessment Questionnaire (HAQ) in SSc. Methods We evaluated 100 patients with SSc followed between 2015 and 2017. All patients were white and fulfilled the American College of Rheumatology/European League Against Rheumatism criteria and/or the Leroy and Medsger (2) criteria for SSc. Mean±SD age at the time of evaluation was 47.66±12.28 years. The mean±SD disease duration was 6.54±6.23 years. Forty-one (41%) patients had diffuse cutaneous SSc and 59 (59%) had limited cutaneous SSc. Global hand and wrist mobility were evaluated using the hand functional index (HFI) and Kapandji index. Global disability and hand disability were assessed by an Arabic and adapted version of the HAQ and by the Arab hand functional index, an Arabic and adapted version of the CHFS, respectively. Anxiety and depression significant symptoms were assessed with the Arabic version of Hospital Anxiety and Depression Scale (HADS) anxiety and HADS depression. Construct validity was assessed by convergent and divergent validity (Spearman’s rank correlation coefficient) and factor analysis. Results The AHFI had correct convergent validity with global disability assessed by the HAQ (0.61) and the HFI (0.55), moderate correlation with the Kapandji Index (-0.48: inverse correlation), depression (HADd) (0.45) and anxiety (HADa) (0.42) and no correlation with the disease duration (0.29) and the age (0.19) (Table 1). Factor analysis (Table 2) extracted 2 factors that accounted for 64.45% of the total variance. The HAQ has a good correlation with hand disability (AHF: 0.61), anxiety (0.57) and the HFI (0.51), a moderate correlation with depression (0.47) and Kapandji index (-0.46) and a little correlation with the age (0.28) and the disease duration (0.10) (Table 1).The factor analysis of the HAQ, extracted 1 factor that accounted for 50.64% of the total variance (Table 2). Conclusion In patients with SSc, the AHFI and the Arabic HAQ have good construct validity. The total score of the AHFI explained 61% of the variance of the HAQ. Acknowledgement All the patients who participated in this study Disclosure of Interests Nouria Benmostefa: None declared, Samy Slimani: None declared, Samir Raoubhia: None declared, Daoud Roula Speakers bureau: Yes, Luc Mouthon: None declared, Rechid Malek: None declared