3D printing of nerve conduits with nanoparticle-encapsulated RGFP966

Xin Xu,Jie Tao,Shuai Wang,Ling Yang,Jiumeng Zhang,Jing Zhang,Haofan Liu, Hao Cheng,Jianguo Xu,Maling Gou,Yuquan Wei

Applied Materials Today（2019）

引用 42|浏览31

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摘要

•A 3D-printed nerve conduit is functionalized with RGFP966 nanoparticles for local treatment.•The RGFP966 promotes the remyelination of Schwann cells by PI3K–AKT–ERK pathway.•The functional conduits provide favorable microenvironment to facilitate the connection of injured nerves.

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关键词

3D bioprinting,Nerve conduits,Nanoparticles,Sciatic nerve,Functional restoration

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