Target Organ Damage In Hypertensive Patients Of The Iberican Study

Objective: The general aim of IBERICAN study is to know the prevalence and incidence of cardiovascular risk factors and cardiovascular and renal disease in Spain. The aim of this abstract is to know the prevalence of subclinical target organ damage (TOD) in hypertensive patients respect non hypertensive patients in the population of the IBERICAN Study. Design and method: The IBERICAN Study is a longitudinal, observational, and multicentric study with subjects between 18 to 85 years of age, recruited in Primary Care (PC) and who will be follow up at least 5 years. The final sample size is estimated in 7.000 patients. We show the baseline characteristics of the patients in the first visit (n = 7,121). To define the TOD, we consider the ESH 2013 Guide criteria: pressure pulse in aged >60 mmHg, ankle/brachial index <0.9, microalbuminuria: albumin/creatinine ratio (between 30 - 299 mg/g), glomerular filtration (CDK-EPI < 60 ml/min), left ventricular hypertrophy (electrocardiogram or ECHO). Results: 3,445 hypertensive patients (prevalence: 48.3%), the mean age in the sample was 65.1 ± 11 years, 49.3% women, antiquity of hypertension of HT 9.5 ± 6.9 years, body mass index 31.1 ± 9.3 kg / m2. Prevalence of TOD in hypertensive vs no hypertensive patients was 39.1% vs 13.3%, p <0.001. With respect to the type of TOD: pulse pressure at >60 years: 26.7% vs 6.2%, p < 0.001; ankle/arm index <0.9: 2.4% vs 1.2%, p = 0.511, NS; microalbuminuria: 11.6% vs 4.6%, p < 0.001; glomerular filtration rate (CDK-EPI < 60 ml/min): 13.9% vs. 3.2%, p < 0.001; left ventricular hypertrophy: 6.8% vs 1.3%, p < 0.001. Conclusions: Patients with hypertension in Primary Care have higher prevalence of subclinical target organ damage respect no hypertensive patients and for each of the types of the subclinical target organ damage according to the ESH 2013 Guide criteria. Is important the diagnosis of TOD, because they are high-risk cardiovascular patients.