Microglia along sex lines: From brain colonization, maturation and function, to implication in neurodevelopmental disorders

Maude Bordeleau,Micaël Carrier,Giamal N. Luheshi,Marie-Ève Tremblay

Seminars in Cell & Developmental Biology（2019）

Cited 47|Views7

No score

Abstract

•Microglia are crucial for proper brain development.•Neurodevelopmental disorders are associated with microglial alterations.•Both microglia and neurodevelopmental disorders possess a strong sexual dimorphism.•Microglia might be crucial to neurodevelopmental disorders’ sexual dimorphism.

Translated text

Key words

ADHD,ASD,BDNF,BPA,C,C3R,CD,CNTN4,CRP,CSDA,Csf1,Csf1r,CX3CR1,CYBB,E,ER,FGF-2,GATAD2A,GBS,GMP6A,GR,HLA-DR,IBA1,IGF1,IGFBP1,IL,IFITM2,LIF,LRP10,MBP,MCP1,MDD,MHC,MIA,MMP16,MR,MSN,NGF,OPC,P,PGE2,PLP1,POA,Poly I:C,PSMA4,P2RY12,Rhoc,Runx1,Runx1t1,SCZ,SOX,SRY,SVZ,TCF4,TGF-β,TLR,TLR2,TMEM119,TNFα,TSC1,TREM2,TRIF,TYROBP,VZ

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined