The neuroprotective effects of novel estrogen receptor GPER1 in mouse retinal ganglion cell degeneration.
Experimental Eye Research(2019)
Abstract
•The novel estrogen receptor GPER1 expressed in the inner retina.•Activation of GPER1 showed protective effects of RGCs in NMDA induced injury.•PI3K/Akt pathway was involved in the regulatory network of GPER1.•GPER1 activation also showed protective effects in acute ocular hypertension.
MoreTranslated text
Key words
17-β-estradiol,GPER1,RGCs,NMDA,Apoptosis
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined