Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018.

Anne Pohlmann,Donata Hoffmann,Christian Grund,Susanne Koethe, Daniela Hüssy,Simone M Meier,Jacqueline King,Jan Schinköthe,Reiner Ulrich,Timm Harder,Martin Beer

EMERGING INFECTIOUS DISEASES（2019）

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摘要

We genetically characterized highly pathogenic avian influenza virus A(H5N6) Glade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment.

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Germany,H5N5,H5N6,H5N8,H5Nx,HPAI,clade 2.3.4.4b,epizootic,ferret model,highly pathogenic avian influenza,influenza,reassortment,respiratory infections,viruses,zoonoses,zoonotic potential

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