Spatial Temporal Clustering of Multi- and Extensively Drug Resistant Tuberculosis is Associated with HIV Status and Drug-susceptibility Pattern in KwaZulu-Natal, South Africa.

Allison Wolf,Nesri Padayatchi,Kogieleum Naidoo,Iqbal Master,Barun Mathema,Max R O'Donnell

CLINICAL INFECTIOUS DISEASES（2020）

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摘要

Using an open-access spatiotemporal analytics program, we mapped spatiotemporal heterogeneity loci in tuberculosis (TB) cases (clusters) and dynamic changes, and characterized the drug-resistant TB clustering risk using routine microbiological data from KwaZulu-Natal, South Africa. The data may provide insight into transmission dynamics and support efficient deployment of public health resources.

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关键词

drug-resistant tuberculosis,HIV,South Africa,spatiotemporal analysis,SatScan

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