Scalable Control Of Asynchronous Boolean Networks
COMPUTATIONAL METHODS IN SYSTEMS BIOLOGY (CMSB 2019)(2019)
摘要
We summarise our recent research results on developing efficient and scalable control methods for gene regulatory networks modelled as asynchronous Boolean networks. Our methods compute a minimal subset of nodes of a given Boolean network, such that (different types of) perturbations of these nodes, in one step or a sequence of steps, can drive the network (from an initial state) to a target steady state.
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