Scalable Control Of Asynchronous Boolean Networks

COMPUTATIONAL METHODS IN SYSTEMS BIOLOGY (CMSB 2019)(2019)

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摘要
We summarise our recent research results on developing efficient and scalable control methods for gene regulatory networks modelled as asynchronous Boolean networks. Our methods compute a minimal subset of nodes of a given Boolean network, such that (different types of) perturbations of these nodes, in one step or a sequence of steps, can drive the network (from an initial state) to a target steady state.
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