Fusobacterium nucleatum bacteremia with pneumopathy in a patient receiving eculizumab: a case report.

Jean Seibel,Jean-Michel Rebibou,Pierre-Henri Bonnot, Anna Bernard, Gilbert Zanetta, Jennifer Tetu,Mathieu Legendre

Anaerobe(2020)

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摘要
Fusobacterium nucleatum is a common oral commensal bacterium capable of severe invasive infections. We report a case of a diffuse bilateral pneumopathy with F. nucleatum-positive blood culture successfully treated by common antibiotics in a patient receiving eculizumab for a drug-induced thrombotic microangiopathy (TMA). It is the first described case of a severe F. nucleatum-associated infection in a patient undergoing terminal complement inhibitor therapy. We suggest providing preventive dental care before eculizumab initiation.
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关键词
Fusobacterium nucleatum,Pneumopathy,Eculizumab,Periodontitis
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