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Identification of HSP90C as a substrate of E3 ligase TaSAP5 through ubiquitylome profiling

Plant Science(2019)

Cited 13|Views11
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Abstract
•HSP90s were identified to be substrates of TaSAP5 using two independent methods.•TaSAP5 interacts with HSP90C and facilitates their ubiquitination in vivo.•TaSAP5 promotes degradation of HSP90C protein via the 26S proteasome.
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Key words
SAP,HSP90C,2-DE,MS,di-Gly-Lys,RABE1B,TUA4,ATPA,CPN60A,GO,HSF,ER
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