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Identification of a Novel Allosteric GLP-1R Antagonist HTL26119 Using Structure- Based Drug Design

Alistair O'Brien,Steve Andrews,Asma H. Baig,Andrea Bortolato,Alastair J. H. Brown,Giles A. Brown, Sue H. Brown,John A. Christopher,Miles Congreve,Robert M. Cooke,Chris De Graaf,James C. Errey,Charlotte Fieldhouse,Ali Jazayeri,Fiona H. Marshall,Jonathan S. Mason,Juan Carlos Mobarec,Krzysztof Okrasa, Kelly N. Steele,Stacey M. Southall,Iryna Teobald,Steve P. Watson,Malcolm Weir

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2019）

Cited 5|Views62
Key words
GLP-1R,GCGR,Allosteric antagonist,HTL26119
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