Higher IL-6 peri-tumoural expression is associated with gastro-intestinal neuroendocrine tumour progression.

Sofia S Pereira,Rúben Pereira,Ana P Santos,Madalena M Costa,Tiago Morais,Paula Sampaio,Bianca Machado,Luís Pedro Afonso,Rui Henrique,Mariana P Monteiro

Pathology（2019）

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摘要

An association of well-differentiated gastroenteropancreatic neuroendocrine tumours (WD GEP NETs) with metabolic syndrome (MetS) was recently described. Yet no molecular mechanisms linking the two conditions are known. This study's aim was to identify putative molecular signatures linking WD GEP NETs and MetS to gain further insight into potential mechanisms for this association.

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Gastrointestinal neuroendocrine tumours,pancreatic neuroendocrine tumours,gastroenteropancreatic neuroendocrine tumours,metabolic syndrome,inflammation

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