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Reproducibility of Ocular Surface Staining in the Assessment of Sjögren Syndrome-Related Keratoconjunctivitis Sicca: Implications on Disease Classification.

Astrid Rasmussen,Donald U Stone,C Erick Kaufman,Kimberly S Hefner,Nicole R Fram,Rhea L Siatkowski,Andrew J W Huang,James Chodosh,Pablo T Rasmussen,Dustin A Fife,Nathan Pezant,Kiely Grundahl,Lida Radfar,David M Lewis,Michael H Weisman,Swamy Venuturupalli,Daniel J Wallace,Nelson L Rhodus,Michael T Brennan,Courtney G Montgomery,Christopher J Lessard,R Hal Scofield,Kathy L Sivils

ACR open rheumatology（2019）

Cited 9|Views26
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Abstract
Ocular surface staining scores are useful for SS research classification; however, they are subject to significant interrater and intrasubject variability, which could result in changes in classification in 5%-10% of all subjects. These results highlight the need for objective and reproducible markers of disease that have thus far remained elusive for SS.
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Key words
syndrome–related keratoconjunctivitis sicca,sjögren syndrome–related,ocular surface staining,disease classification
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