Efficacy of imidacloprid 10%/moxidectin 2.5% spot on (Advocate®, Advantage Multi®) and doxycycline for the treatment of natural Dirofilaria immitis infections in dogs.
Veterinary Parasitology(2019)
摘要
•Combination treatment with moxidectin and doxycycline is adulticidal in dogs naturally infected with D. immitis.•Efficacy is 100% at 9 months from the beginning of treatment.•Efficacy for elimination of microfilariae is 99.9% after 1 month from the beginning of treatment.•Treatment is well tolerated and non-inferior to melarsomine at 12, 18 and 24 month from the beginning of treatment.
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关键词
Dirofilaria immitis,Dog,Moxidectin,Doxycycline,Melarsomine dihydrochloride
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