Chemotaxonomy and cytotoxicity of the liverwort Porella Viridissima
Natural Product Research(2019)
Abstract
The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesquiterpenes are reported for the first time in liverwort. P. viridissima was found to belong to the chemotype III (pinguisane/sacculatane) and shared chemical similarities with P. navicularis. Perrotettianal A was isolated and has shown strong cytotoxicity against ovarian cancer.
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Key words
Liverwort,Porella viridissima,chemotype,pinguisane,sacculatane,ovarian cancer
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