Effects of vitamin D supplementation on circulatory YKL-40 and MCP-1 biomarkers associated with vascular diabetic complications: A randomized, placebo-controlled, double-blind clinical trial.

Mahsa Omidian,Maryam Mahmoudi,Mohammad Hassan Javanbakht,Mohammad Reza Eshraghian,Maryam Abshirini,Elnaz Daneshzad,Hossein Hasani,Ehsan Alvandi,Mahmoud Djalali

Diabetes & Metabolic Syndrome: Clinical Research & Reviews（2019）

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摘要

Daily vitamin D supplementation effectively reduced circulatory YKL-40 and MCP-1 levels in patients with type-2 diabetes and vitamin D deficiency. Vitamin D might contribute in reducing diabetic complications via modulating YKL-40 and MCP-1 signaling pathways.

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关键词

Vitamin D,Diabetic complications,YKL-40,Monocyte chemoattractant protein-1,Inflammation

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