Recurrent inflammatory disease caused by a heterozygous mutation in CD48.

Benjamin Volkmer,Raquel Planas, Emanuel Gossweiler, Anna Lünemann,Lennart Opitz,Andrea Mauracher,Ursina Nüesch,Tenzin Gayden,Daniela Kaiser, Barbara Drexel,Claudia Dumrese,Nada Jabado,Stefano Vavassori,Jana Pachlopnik Schmid

The Journal of allergy and clinical immunology（2019）

引用 11|浏览24

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摘要

Sufficient cell surface expression of CD48 is needed to (i) control inflammation, (ii) ensure correct natural killer cell maturation and function, and (iii) regulate target cell susceptibility to cytotoxicity.

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