Sample Size Calculation Guide - Part 4: How to Calculate the Sample Size for a Diagnostic Test Accuracy Study based on Sensitivity, Specificity, and the Area Under the ROC Curve.

In the previous educational articles, we explained how to calculate the sample size for a rate or a single proportion (part 1), for an independent cohort study (part 2), and for an independent case-control study (part 3). In this article, we will explain how to calculate the sample size for a diagnostic test accuracy study based on sensitivity, specificity, or the area under the ROC curve.