Whole-heart T 1 mapping using a 2D fat image navigator for respiratory motion compensation.
MAGNETIC RESONANCE IN MEDICINE(2020)
摘要
Purpose: To combine a 3D saturation-recovery-based myocardial T-1 mapping (3D SASHA) sequence with a 2D image navigator with fat excitation (fat-iNAV) to allow 3D T-1 maps with 100% respiratory scan efficiency and predictable scan time. Methods: Data from T-1 phantom and 10 subjects were acquired at 1.5T. For respiratory motion compensation, a 2D fat-iNAV was acquired before each 3D SASHA k-space segment to correct for 2D translational motion in a beat-to-beat fashion. The effect of the fat-iNAV on the 3D SASHA T1 estimation was evaluated on the T-1 phantom. For 3 representative subjects, the proposed free-breathing 3D SASHA with fat-iNAV was compared to the original implementation with the diaphragmatic navigator. The 3D SASHA with fat-iNAV was compared to the breath-hold 2D SASHA sequence in terms of accuracy and precision. Results: In the phantom study, the Bland-Altman plot shows that the 2D fat-iNAVs does not affect the T-1 quantification of the 3D SASHA acquisition (0 +/- 12.5 ms). For the in vivo study, the 2D fat-iNAV permits to estimate the respiratory motion of the heart, while allowing for 100% scan efficiency, improving the precision of the T-1 measurement compared to non-motion-corrected 3D SASHA. However, the image quality achieved with the proposed 3D SASHA with fat-iNAV is lower compared to the original implementation, with reduced delineation of the myocardial borders and papillary muscles. Conclusions: We demonstrate the feasibility to combine the 3D SASHA T-1 mapping imaging sequence with a 2D fat-iNAV for respiratory motion compensation, allowing 100% respiratory scan efficiency and predictable scan time.
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关键词
fat image navigator,myocardial T-1 mapping,respiratory motion compensation
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