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rhEPO inhibited cell apoptosis to alleviate acute kidney injury in sepsis by AMPK/SIRT1 activated autophagy.

Kan Li,Tian-Xi Liu,Jun-Feng Li,Yan-Rong Ma,Ming-Long Liu,Yi-Qing Wang,Rong Wu,Bin Li,Long-Zhen Shi,Cheng Chen

Biochemical and Biophysical Research Communications（2019）

Cited 30|Views13
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Abstract
•rhEPO inhibits LPS-induced cell apoptosis by activating autophagy.•rhEPO activates autophagy via the AMPK/SIRT1 pathway.•rhEPO prevents LPS-induced acute kidney injury.
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Key words
rhEPO,Autophagy,Apoptosis,SIRT1,AMPK
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