Current Surgical Approaches In Takayasu'S Arteritis: A Single-Centre Experience

Clinical and experimental rheumatology(2020)

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Abstract
Objective. We investigated cardiovascular surgical interventions in a group of patients with Takayasu's arteritis (TAK) diagnosed and followed by a single centre.Methods. Twenty patients with TAK (5 males, 15 females, mean current age: 38.1 +/- 10.7) who were operated,for a broad spectrum of cardiovascular diseases ranging from coronary heart disease to coeliac stenosis or aneurysm between July 2008 and April 2016 were studied. One patient underwent operation related to aneurysm of ascending aorta and aortic insufficiency, 2 patients had operations for both coronary arteries originating from aortic arch, 6 patients for only arteries originating from aortic arch, 1 patient for both carotid and infra-inguinal artery, 5 patients,for aorta-iliac or femoral revascularisation, 5 patients for renal artery and/or coeliac or superior mesenteric artery re vascularisations. Three of these interventions were endarterectomy and patch plasty.Results. The mean time between diagnosis and surgical intervention was 6.1 +/- 3.1 years (range: 3 months-12 years). A total of 4/32 (12.5%) grafts were occluded during the follow, up period of mean 39.2 +/- 24.6 months. Secondary interventions like cross femoral, or graft to superficial femoral artery bypasses were needed in 2 patients who underwent aorta-bifemoral bypasses to keep patency. There was no operative mortality. We did not observe any anastomotic aneurysm. One patient died due to graft infection 3 months after the operation. Stroke occurred in 2 patients who underwent revascularisations of the arteries originating from aortic arch.Conclusion. In our series, we have a relatively good midterm patency rates in patients with TAK and did not observe any anastomotic psettdoanettrysin. Stroke developed in 2 patients and mortality occurred in one patient due to the graft infection 3 months after the operation. In patients with limited carotid or aortailiac stenosis, chance,for endarterectomy should be evaluated. Well-controlled disease activity with intensive medical treatment and multi-disciplinary approach could be associated with a favourable long-term outcome.
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Key words
Takayasu's arteritis, surgery, revascularisation, graft, bypass
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