URB597 ameliorates the deleterious effects induced by binge alcohol consumption in adolescent rats.

Paula M Q Bellozi,Renan Pelição,Matheus C Santos,Isabel V A Lima,Soraya W Saliba,Érica L M Vieira,Alline C Campos,Antônio L Teixeira,Antônio C P de Oliveira,Ester M Nakamura-Palacios,Lívia C M Rodrigues

Neuroscience Letters（2019）

引用 13|浏览21

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摘要

•URB597 prevents long-term memory deficits induced by lower dose of alcohol acute binge drinking.•URB597 prevents cytokines changes induced by alcohol chronic binge in prefrontal cortex and hippocampus.•URB597 prevents BDNF increase induced by alcohol chronic binge in prefrontal cortex.

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关键词

Alcohol binging,Neuroinflammation,Adolescence,Endocannabinoid system,URB597

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