Loss of retinal tension and permanent decrease in retinal function: a new porcine model of rhegmatogenous retinal detachment.

Acta ophthalmologica(2020)

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摘要
Loss of retinal tension in the detached retina seems to induce permanent damage with loss of retinal function. Death of ganglion cells, observed as soon as 2 weeks after detachment, explains the permanent loss of retinal function. The new model enables investigations of time-relationship between retinal detachment and lasting damage in addition to exploration of novel treatment modalities.
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关键词
Neuroprotection,RPE damage,animal model,intermediate filaments,mammal,retinal surgery,subretinal surgery
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